Techh.info/biomedtechnology hourly

CRISPR

headlines texts
09.12.2019
19:55 ScienceDaily.comGenomic cut and paste using a Class 1 CRISPR system

Repairing faulty genes to prevent and cure disease is something researchers have been working towards for many years. While Class 2 CRISPR systems show great promise as gene editing tools in human cells, a research team has now demonstrated that a Cas3-based Class 1 CRISPR system may provide a more efficient and safer alternative, carrying out successful repair of a gene mutation responsible for Duchenne muscular dystrophy in patient-derived cells.

Скрыть анонс
19:16 Nature.ComA bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases

Скрыть анонс
19:09 Phys.orgCRISPR-resistant viruses build 'safe rooms' to shield genomes from DNA-dicing enzymes

Bacteria and the viruses that infect them are engaged in a molecular arms race as ancient as life itself. Evolution has equipped bacteria with an arsenal of immune enzymes, including CRISPR-Cas systems, that target and destroy viral DNA. But bacteria-killing viruses, also known as phages, have devised their own tools to help them outmaneuver even the most formidable of these bacterial defenses.

Скрыть анонс
17:10 Phys.orgGenomic cut and paste using a class 1 CRISPR system

Almost from the moment DNA was discovered, the ability to fix or remove disease-causing genes in affected patients has been something of a holy grail of medicine. Now that this goal is within reach, researchers are working to fine-tune the technology to ensure safe and effective gene editing with no unwanted downstream effects.

Скрыть анонс
06.12.2019
23:09 News-Medical.NetNew tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

Amidst rising hopes for using CRISPR gene editing tools to repair deadly mutations linked to conditions like cystic fibrosis and sickle cell disease, a new study in the Nature journal Communications Biology describes a new innovation that could accelerate this work by rapidly revealing unintended and potentially harmful changes introduced by a gene editing process.

Скрыть анонс
17:31 Phys.orgNew tool for rapidly analyzing CRISPR edits reveals frequent production of unintended edits

Amidst rising hopes for using CRISPR gene editing tools to repair deadly mutations linked to conditions like cystic fibrosis and sickle cell disease, a study in Communications Biology describes a new innovation that could accelerate this work by rapidly revealing unintended and potentially harmful changes introduced by a gene editing process.

Скрыть анонс
04.12.2019
17:55 Technology.orgWill CRISPR-Cas9 Help Biohacker to Be Next Captain America

In the marvel universe, a short and thin guy named Rogers underwent a series of gene transformations and

Скрыть анонс
17:13 News-Medical.NetExperts condemn Chinese CRISPR babies research as original manuscript is made public

Scientists have criticized the gene-editing of the Chinese twins last year, following the first public release of the research.

Скрыть анонс
03.12.2019
23:08 News-Medical.NetZebrafish study supports accuracy of CRISPR-Cas9 gene editing tool

Along with the promise that CRISPR-Cas9 gene editing technology can offer new human therapies is the need to ensure its safety. A recent study showed that CRISPR-Cas9 did not produce off-target gene mutations in zebrafish. These results, published in Frontiers in Genetics, confirm previous data in animal models that the risk to the rest of the genome from gene editing is minimal.

Скрыть анонс
20:58 Nature.ComDaily briefing: The unpublished CRISPR-babies papers

Скрыть анонс
13:08 TechnologyReview.comOpinion: We need to know what happened to CRISPR twins Lulu and Nana

The unpublished research paper by He Jiankui about the creation of the babies shows proof of attempted gene editing gone awry.

Скрыть анонс
13:08 TechnologyReview.comWhy the paper on the CRISPR babies stayed secret for so long

The report describing the creation of the world’s first gene-edited babies creates an ethical quandary for scientific journals.

Скрыть анонс
13:08 TechnologyReview.comChina’s CRISPR babies: Read exclusive excerpts from the unseen original research

He Jiankui’s manuscript shows how he ignored ethical and scientific norms in creating the gene-edited twins Lulu and Nana.

Скрыть анонс
03:45 Yahoo ScienceCyrus Biotechnology and CRISPR pioneers team up to boost gene-editing therapies

Seattle-based Cyrus Biotechnology says it'll collaborate with the Broad Institute of MIT and Harvard on ways to optimize CRISPR gene-editing techniques for use in developing novel human therapeutics. CRISPR has revolutionized genetics by making it easier to modify the DNA coding in the genome, but more needs to be done to address safety concerns for human applications. Cyrus Biotech and the Broad Institute will work on ways to reduce the potential for the body to mount an immune response against CRISPR-based therapies. MIT biochemist Feng Zhang, one of the pioneers in the development of CRISPR, will be the principal investigator… Read More

Скрыть анонс
02.12.2019
16:34 Phys.orgHarnessing the power of CRISPR in space and time

Researchers in Vienna from Ulrich Elling's laboratory at IMBA—Institute of Molecular Biotechnology of the Austrian Academy of Sciences—in collaboration with the Vienna BioCenter Core Facilities have developed a revolutionary CRISPR technology called "CRISPR-Switch," which enables unprecedented control of the CRISPR technique in both space and time.

Скрыть анонс
16:21 FierceBiotech.comCyrus, the Broad team up to make in vivo CRISPR use safer

Cyrus Biotechnology has teamed up with the Broad Institute to optimize CRISPR for use in humans. Feng Zhang, who had a hand in developing CRISPR, will serve as the Broad’s principal investigator for the collaboration. 

Скрыть анонс
29.11.2019
13:55 Nanowerk.comHarnessing the power of CRISPR in space and time

Scientists have developed a revolutionary CRISPR technology called ?CRISPR-Switch?, which enables unprecedented control of the CRISPR technique in both space and time.

Скрыть анонс
25.11.2019
22:12 News-Medical.NetNew electrochemical CRISPR biosensor can help improve diagnosis of diseases

The CRISPR/Cas technology can do more than alter genes. A research team at the University of Freiburg is using what are known as gene scissors - which scientists can use to edit genetic material - in order to better diagnose diseases such as cancer.

Скрыть анонс
20.11.2019
18:24 News-Medical.NetPioneering CRISPR therapy leaves two patients free of blood disease symptoms

The first two clinical trials for CRISPR-based treatments for inherited blood disorders have been successful.

Скрыть анонс
19.11.2019
22:13 TechnologyReview.comCompanies declare signs of success in CRISPR treatment of blood disorders

Скрыть анонс
15.11.2019
16:56 Phys.orgNew twist on CRISPR technology

In a classic episode of an old-school TV comedy called I Love Lucy, we see Lucille Ball stepping into an assembly line job at a candy factory. As the pace of the conveyor belt exceeds her ability to wrap the candy, the frenzy gets the best of her. She shoves candy into her pockets, into her hat, into her mouth—it's a job fail.

Скрыть анонс
14:48 TechnologyReview.comCRISPR has made Jennifer Doudna rich. Now she says it must be controlled.

Скрыть анонс
13.11.2019
20:20 Medscape.ComCRISPR Used to Silence Crucial Hepatitis B Gene

A new CRISPR technology used to target a gene might be an effective way to eradicate chronic hepatitis B infection, investigators report.

Скрыть анонс
10:08 Technology.orgCRISPR: More than just for gene editing?

The gene-editing tool CRISPR has been heralded as a scientific miracle destined to eradicate diseases from sickle-cell anemia

Скрыть анонс
12.11.2019
17:28 Phys.orgUsing CRISPR for dose-dependent activation of gene expressions

A team of researchers affiliated with several institutions in the U.S. has developed a way to use the CRISPR gene editing technique for dose-dependent activation of gene expressions. In their paper published in the journal Nature Biotechnology, the group describes their technique for altering gene expression in an alternative way and how well it worked.

Скрыть анонс
11.11.2019
18:11 ScienceDaily.comCRISPR: More than just for gene editing?

Researchers have converted the CRISPR 'recognition induced enzymatic signal' to an electrical signal, which was then used to detect the biomarkers for viruses such as HPV or parvo. They hope the end result could be a new 'universal biosensing' point-of-care medical device -- similar to the existing commercial blood-glucose sensor -- that rapidly and accurately detects those viruses and more.

Скрыть анонс
16:32 Nature.ComCRISPR tool modifies genes precisely by copying RNA into the genome

Скрыть анонс
14:38 Nature.ComCRISPR: the movie

Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and how science impacts upon all aspects of society and life.

Скрыть анонс
11:14 Phys.orgCRISPR: More than just for gene editing?

The gene-editing tool CRISPR has been heralded as a scientific miracle destined to eradicate diseases from sickle-cell anemia to cancer, or decried as "the genetic scissors that tailor the human gene pool," an ethically risky technology driving us toward a designer babies.

Скрыть анонс
00:20 ScienceDaily.comModified CRISPR gene editing tool could improve therapies for HIV, sickle cell disease

Researchers may have found a way to sharpen the fastest, cheapest and most accurate gene editing technique, CRISPR-Cas9, so that it can more successfully cut out undesirable genetic information. This improved cutting ability could one day fast-track potential therapies for HIV, sickle cell disease and, potentially, other immune conditions.

Скрыть анонс
08.11.2019
13:22 Technology.orgEarly Results from First-In-U.S. Trial of CRISPR-Edited Immune Cells for Cancer Patients Suggest Safety of Approach

Genetically editing a cancer patient’s immune cells using CRISPR/Cas9 technology, then infusing those cells back into the patient

Скрыть анонс
00:35 Phys.orgModified CRISPR gene editing tool could improve therapies for HIV, sickle cell disease

City of Hope researchers may have found a way to sharpen the fastest, cheapest and most accurate gene editing technique, CRISPR-Cas9, so that it can more successfully cut out undesirable genetic information.

Скрыть анонс
07.11.2019
19:18 ScienceDaily.comA new CRISPR-Cas9 protein to increase precision of gene editing

Researchers have recently developed a new protein that can help increase the targeting accuracy in the genome editing process. It is believed that it would be useful for future gene therapies in humans, which require high precision.

Скрыть анонс
18:34 FierceBiotech.comASH: UPenn’s CRISPR-edited immune cells prove safe in small cancer study

Three years after tech billionaire Sean Parker's Institute for Cancer Immunotherapy became the first research institution to launch a human trial of CRISPR-edited cells in cancer, the scientists running that trial are reporting that the therapy has been well tolerated by three patients.

Скрыть анонс
01:18 LiveScience.comDoctors Are Trying to Use CRISPR to Fight Cancer. The 1st Trial Suggests It's Safe.

Preliminary data from an innovative clinical trial suggests CRISPR could be safe for use in cancer therapy.

Скрыть анонс
06.11.2019
21:38 News-Medical.NetCRISPR-Cas9 protein can help increase targeting accuracy in genome editing process

A team of researchers from City University of Hong Kong and Karolinska Institutet has recently developed a new protein that can help increase the targeting accuracy in the genome editing process. It is believed that it would be useful for future gene therapies in human, which require high precision.

Скрыть анонс
20:23 Phys.orgA new CRISPR-Cas9 protein to increase precision of gene editing

A team of researchers from City University of Hong Kong (CityU) and Karolinska Institutet has recently developed a new protein that can help increase the targeting accuracy in the genome editing process. It is believed that it would be useful for future gene therapies in humans, which require high precision.

Скрыть анонс
18:16 News-Medical.NetGene-editing technique CRISPR trialed for first time as cancer treatment

The go-ahead has been given for the first trials using CRISPR as an alternative therapy for treating cancer.

Скрыть анонс
05.11.2019
18:05 SingularityHub.ComEverything You Need to Know About Superstar CRISPR Prime Editing

All right, let’s do this one last time. My name is CRISPR. I was made from a bacterial defense system, and for years I’ve been the one and only gene editing wunderkind. I’m pretty sure you know the rest. I’m relatively cheap to make, easy to wield, and snip out genes pretty on target. I’m […]

Скрыть анонс
13:45 Nature.ComInclude egg donors in CRISPR gene-editing debate

Скрыть анонс
30.10.2019
17:04 News-Medical.NetImproved Cas9 enzyme reduces chance of off-target CRISPR mutations

Genomics experts have discovered that when guide RNAs (gRNA) are designed properly, the risk of off-target mutations induced by the cas9 enzyme is very rare.

Скрыть анонс
29.10.2019
20:11 Nature.ComA crop that feeds billions freed from blight by CRISPR

Скрыть анонс
25.10.2019
23:33 ScienceMag.orgTop stories: Life after dinosaurs, Neanderthal planning, and Russia’s CRISPR babies

This week’s top Science news

Скрыть анонс
23.10.2019
20:15 Nature.ComBacterial biodiversity drives the evolution of CRISPR-based phage resistance

Скрыть анонс
13:56 ScientificAmerican.ComScientists Program CRISPR to Fight Viruses in Human Cells

A common gene editing enzyme could be used to disable RNA viruses such as flu or Ebola -- Read more on ScientificAmerican.com

Скрыть анонс
06:48 News-Medical.NetNew CRISPR genome “prime editing” system

Gene editing to correct genetic faults and removing the risk of hereditary diseases may soon become reality. Researchers have come up with a new gene editing technology that could help patients with sickle cell anaemia and up 89 percent of other genetic defects.

Скрыть анонс
22.10.2019
20:08 Geek.comBreakthrough Gene-Editing Tool is Better Than CRISPR

(via Kate Whitley/Wellcome Collection) A team from MIT and Harvard developed a new CRISPR genome-editing approach that can make extremely precise DNA edits. The breakthrough tool, known as prime editing, has the potential to correct up to […]
The post Breakthrough Gene-Editing Tool is Better Than CRISPR appeared first on Geek.com.

Скрыть анонс
17:16 SingularityHub.ComCRISPR Just Created a Hornless Bull, and It’s A Step Forward for Gene-Edited Food

There’s a practice in farming not often talked about. To prevent accidental harm to human handlers and other cattle, bulls generally have their horn-producing cells surgically removed before the horns permanently attach to their skull. Although it’s a common practice, de-horning is a morally-icky procedure that causes additional pain to farm animals, and advocates have […]

Скрыть анонс
21.10.2019
20:08 ScienceDaily.comNew CRISPR genome editing system offers a wide range of versatility in human cells

A team has developed a new CRISPR genome-editing approach by combining two of the most important proteins in molecular biology -- CRISPR-Cas9 and a reverse transcriptase -- into a single machine.

Скрыть анонс
20:01 Phys.orgNew CRISPR genome editing system offers a wide range of versatility in human cells

A team from the Broad Institute of MIT and Harvard has developed a new CRISPR genome-editing approach by combining two of the most important proteins in molecular biology—CRISPR-Cas9 and a reverse transcriptase—into a single machine.

Скрыть анонс
19:48 FierceBiotech.comBayer backs off running Casebia JV, as CRISPR Tx takes over management

Three years after Bayer and gene-editing biotech CRISPR Therapeutics joined forces to launch and run Casebia Therapeutics, the German Pharma is now handing over the full reins of running the biotech to CRISPR.

Скрыть анонс
19:10 ScienceMag.orgNew ‘prime’ genome editor could surpass CRISPR

A more precise, flexible variation of the revolutionary DNA modifier makes its debut

Скрыть анонс
19:06 Nature.ComSuper-precise new CRISPR tool could tackle a plethora of genetic diseases

Скрыть анонс
18:14 NewScientist.ComCRISPR upgrade could make genome editing better and safer

A new variant of CRISPR, dubbed prime editing, should make it even better at correcting disease-causing mutations

Скрыть анонс
18:07 TechnologyReview.comThe newest gene editor radically improves on CRISPR

Researchers have developed a true search-and-replace function for DNA.

Скрыть анонс
19.10.2019
15:02 ScientificAmerican.ComRussian "CRISPR-Baby" Scientist Has Started Editing Genes in Human Eggs with the Goal of Altering Deaf Gene

Denis Rebrikov says that he does not plan to implant gene-edited embryos until he gets regulatory approval -- Read more on ScientificAmerican.com

Скрыть анонс
18.10.2019
10:06 Nature.ComRussian ‘CRISPR-baby’ scientist has started editing genes in eggs from a deaf woman

Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and how science impacts upon all aspects of society and life.

Скрыть анонс
15.10.2019
23:43 News-Medical.NetCRISPR helps find difficult to detect cancer cells

Immunotherapy is one of the latest and most effective armaments against various types of cancers. Some of the immunotherapy drugs such as PD-1 inhibitor Keytruda from Merck can block certain proteins in the cancer cells that can make the cells invisible to the immune system normally. Some of the cancers cells can now develop other ways to disguise themselves from being killed by the immune system.

Скрыть анонс
23:20 LiveScience.comWidely Publicized Study on CRISPR Babies' Gene Mutation Now Retracted for Errors

A widely publicized study that suggested that the first gene-edited "CRISPR" babies could have shorter lifespans has been retracted due to crucial errors in the analysis.

Скрыть анонс
17:10 Phys.orgAAV vector integration into CRISPR-induced DNA breaks

To design safe clinical trials, it is crucial to better understand and predict gene editing outcomes in preclinical studies. Bence György and collaborators have shown that adeno-associated viruses (AAVs) can stably integrate into CRISPR-Cas9-induced double-strand breaks, in up to almost half of the therapeutically targeted cells, in vitro and in vivo in mice. The team also showed that CRISPR did not cause an increase in genome-wide integration of AAV, but only at the CRISPR-cut site.

Скрыть анонс
17:08 News-Medical.NetStudy suggesting that CRISPR babies are likely to die early has been retracted

A research paper that sparked concerns about the lifespan of China's first gene-edited babies has been retracted due to technical errors.

Скрыть анонс
14.10.2019
18:15 FierceBiotech.comMarrying CRISPR with immuno-oncology to defeat remote tumors

Yale scientists have combined the gene-editing system CRISPR with a type of gene therapy designed to help the immune system find tough-to-spot tumor cells. The technology showed promise in mouse models of triple-negative breast cancer, melanoma and pancreatic cancer.

Скрыть анонс
06:39 Nature.ComGeneticists retract study suggesting first CRISPR babies might die early

Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and how science impacts upon all aspects of society and life.

Скрыть анонс
10.10.2019
21:51 ScienceDaily.comCRISPR enzyme programmed to kill viruses in human cells

Researchers have now turned a CRISPR RNA-cutting enzyme into an antiviral that can be programmed to detect and destroy RNA-based viruses in human cells.

Скрыть анонс
19:43 News-Medical.NetCRISPR RNA-cutting enzyme programmed to destroy viruses in human cells

Many of the world's most common or deadly human pathogens are RNA-based viruses -- Ebola, Zika and flu, for example -- and most have no FDA-approved treatments.

Скрыть анонс
18:06 Phys.orgCRISPR enzyme programmed to kill viruses in human cells

Many of the world's most common or deadly human pathogens are RNA-based viruses—Ebola, Zika and flu, for example—and most have no FDA-approved treatments. A team led by researchers at the Broad Institute of MIT and Harvard has now turned a CRISPR RNA-cutting enzyme into an antiviral that can be programmed to detect and destroy RNA-based viruses in human cells.

Скрыть анонс
09.10.2019
19:00 Phys.orgCRISPR-BEST prevents genome instability

Even though CRISPR technologies allow for better manipulation of genomes with many positive effects on modern drug development and the discovery of new and better antibiotics, significant problems such as genome instability and toxicity of the Cas9 protein still remain when using the technology.

Скрыть анонс
18:19 ScienceDaily.comCRISPR-BEST prevents genome instability

Scientists have developed CRISPR-BEST, a new genome editing tool for actinomycetes. It addresses the problem of genome instability caused by DNA double-stranded breaks in current CRISPR-technologies.

Скрыть анонс
04.10.2019
19:02 ScienceDaily.comResearchers unlock potential to use CRISPR to alter the microbiome

Researchers have developed a new way to deliver the DNA-editing tool CRISPR-Cas9 into microorganisms in the lab, providing a way to efficiently launch a targeted attack on specific bacteria.

Скрыть анонс
17:44 Phys.orgResearchers unlock potential to use CRISPR to alter the microbiome

Researchers at Western University have developed a new way to deliver the DNA-editing tool CRISPR-Cas9 into microorganisms in the lab, providing a way to efficiently launch a targeted attack on specific bacteria.

Скрыть анонс
05:25 News-Medical.NetUC Davis researchers awarded $1.5 million NIH grant for CRISPR cancer treatment

What if, instead of killing cancer cells or cells about to become cancerous, you could deliver a repair package and fix them? UC Davis researchers have just been awarded $1.5 million from the National Institutes of Health to start work towards that goal.

Скрыть анонс
03.10.2019
19:24 Nature.ComDaily briefing: Scientists reconstruct butterfly evolutionary history with CRISPR

Скрыть анонс
02.10.2019
14:06 Technology.orgNew CRISPR-Cas9 variant may boost precision in gene editing

Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase

Скрыть анонс
01.10.2019
04:03 News-Medical.NetNew CRISPR-Cas9 variant has potential to increase precision during gene therapy

Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans.

Скрыть анонс
00:04 TechnologyReview.comPutin could decide for the world on CRISPR babies

Скрыть анонс
30.09.2019
22:03 Phys.orgNew CRISPR-Cas9 variant may boost precision in gene editing

Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans. The new variant reduced unintended changes in DNA compared to its wildtype, suggesting it could play a role in gene therapies that require high precision. The study by researchers from Karolinska Institutet's Ming Wai Lau Centre of Reparative Medicine in Hong Kong is published in the journal PNAS.

Скрыть анонс
27.09.2019
20:55 DigitalTrends.comCRISPR-Cas9 gene editing could one day ‘turn off’ HIV virus in the body

A cure for HIV? Researchers from the UC San Diego School of Medicine have proposed a new genetic-sequencing approach that could provide a kill switch to clear out dormant HIV inside cells.

Скрыть анонс
00:40 News-Medical.NetResearcher aims to make CRISPR-Cas9 system safer and more precise

The mere mention of gene editing and DNA altering might conjure up images of designer babies, but that is not what researcher Jin Liu has in mind.

Скрыть анонс
25.09.2019
14:25 Phys.orgNew discoveries map out CRISPR-Cas defense systems in bacteria

For the first time ever, researchers at the University of Copenhagen have mapped how bacterial cells trigger their defense against outside attacks. This could affect how diseases are fought in the future.

Скрыть анонс
01:30 ScienceDaily.comNew CRISPR class expands genetic engineering toolbox

Biomedical engineers have used a previously unexplored CRISPR technology to accurately regulate and edit target genes in human cells. With this new approach, the researchers hope to dramatically expand the CRISPR-based tools available to biomedical engineers, opening up a new and diverse frontier of genome engineering technologies.

Скрыть анонс
24.09.2019
19:21 ScienceDaily.comNew discoveries map out CRISPR-Cas defense systems in bacteria

For the first time ever, researchers have mapped how bacterial cells trigger their defense against outside attacks. This could affect how diseases are fought in the future.

Скрыть анонс
11:50 Nature.ComCRISPR might be the banana’s only hope against a deadly fungus

Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and how science impacts upon all aspects of society and life.

Скрыть анонс
23.09.2019
19:37 News-Medical.NetCRISPR discovery opens up new possibilities for genetic engineering

Scientists have successfully developed a different kind of CRISPR technology, opening up a world of possibility to future developments in the genetic engineering space

Скрыть анонс
18:03 FierceBiotech.comNew CRISPR approach could improve gene and cell therapies

Biomedical engineers at Duke are developing a new CRISPR system designed to alter the epigenome they believe could address some of the shortcomings of CRISPR-Cas9 and be used to perform many different genome engineering tasks simultaneously.

Скрыть анонс
18:03 Phys.orgNew CRISPR class expands genetic engineering toolbox

Biomedical engineers at Duke University have used a previously unexplored CRISPR technology to accurately regulate and edit genomes in human cells.

Скрыть анонс
19.09.2019
01:01 TechnologyReview.comCRISPR could help us cure sickle cell disease. But patients are wary.

How accessible would a cure be to the people who need it?

Скрыть анонс
18.09.2019
13:44 Technology.orgCRISPR portfolio now at 14 and counting

The U.S. Patent and Trademark Office (USPTO) today awarded the University of California (UC), University of Vienna and

Скрыть анонс
16.09.2019
15:57 Technology.orgScientists use CRISPR to Treat HIV for the First Time

The patient in question – a 27-year-old male citizen of China – was diagnosed with AIDS back in

Скрыть анонс
13.09.2019
19:12 News-Medical.NetCRISPR may explain why so many experimental cancer drugs fail

Scientists have used CRISPR–Cas9 to investigate how ten cancer drugs interact with their protein target, revealing some intriguing findings.

Скрыть анонс
10:02 CNN HealthChinese scientists use CRISPR tool on HIV patient for the first time

A Chinese team from Peking University have used gene editing tool CRISPR-Cas9 on a HIV patient for the first time. They managed to create stem cells resistant to the disease, but weren't able to cure him.

Скрыть анонс
12.09.2019
19:58 News-Medical.NetScientists attempt to cure HIV using CRISPR, with varying results

Scientists have used the gene-editing technology CRISPR in an attempt to cure a person infected with HIV, with some success.

Скрыть анонс
01:00 LiveScience.comChinese Scientists Tried to Treat HIV Using CRISPR

Scientists in China have attempted to use CRISPR gene-editing technology to treat a patient with HIV.

Скрыть анонс
11.09.2019
22:13 ScienceMag.orgSome cancer drugs miss their target. CRISPR could improve their aim

Method that generated drug leads may be flawed

Скрыть анонс
09.09.2019
16:40 Phys.orgGenome engineering with CRISPR/HDR to diversify the functions of hybridoma-produced antibodies

Bioengineers and life scientists incorporate hybridoma technology to produce large numbers of identical antibodies, and develop new antibody therapeutics and diagnostics. Recent preclinical and clinical studies on the technology highlight the importance of antibody isotypes for therapeutic efficacy. In a new study, a research team in Netherlands have developed a versatile Clustered Regularly Interspaced Short Palindrome Repeats (CRISPR) and homology directed repair (HDR) platform to rapidly engineer immunoglobin domains and form recombinant hybridomas that secrete designer antibodies of a preferred format, species or isotype. In the study, Johan M. S. van der Schoot and colleagues at the interdisciplinary departments of immunology, proteomics, immunohematology, translational immunology and medical oncology, used the platform to form recombinant hybridomas, chimeras and mutants. The stable

Скрыть анонс
04.09.2019
17:48 SingularityHub.ComCellular Computers Get a Boost with CRISPR

Cancer’s impenetrable secrets partly rely on its mysterious molecular history. As cells turn to the dark side, a whirlwind of DNA changes gradually accumulate. Like flipping multiple interlinked light switches, the cell gradually changes its internal molecular operations, until its once-beneficial nature turns malevolent. Why, when, and how this sinister transformation happens is still unknown, […]

Скрыть анонс
15:38 ScientificAmerican.ComA CRISPR Doyen Discusses Gene-Editing Challenges

Jennifer Doudna, winner of the 2018 Kavli Prize in Nanoscience, talks to Scientific American about what it’s like to work in perhaps the hottest research area in all of biology. She also... -- Read more on ScientificAmerican.com

Скрыть анонс
03.09.2019
17:00 News-Medical.NetCRISPR-Cas9 successfully reverses type 2 diabetes in mice

Researchers have used CRISPR-Cas9 to treat obesity and type 2 diabetes in mice, a development that could eventually benefit humans.

Скрыть анонс
16:28 Phys.orgNovel CRISPR method identifies key genes for Toxoplasma survival

Using a new approach to genetic screening with CRISPR, researchers at the Crick have identified key genes for the survival of the parasite Toxoplasma gondii in mice.

Скрыть анонс
02.09.2019
18:49 News-Medical.NetSATI gene editing could replace CRISPR

Scientists have developed a new gene editing tool called SATI that is safer than CRISPR.

Скрыть анонс
01.09.2019
14:19 NewScientist.ComCRISPR could lead to gene-editing fix for a form of male infertility

Infertile male mice have fathered offspring after their condition was fixed by CRISPR – an approach that could help many couples with fertility problems

Скрыть анонс
First← Previous123Previous →Last