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12.07.2020
00:23 ScienceDaily.comExtraordinary regeneration of neurons in zebrafish (4)

Biologists have discovered a uniquely rapid form of regeneration in injured neurons and their function in the central nervous system of zebrafish. They studies the Mauthner cells, which are solely responsible for the escape behavior of the fish, and previously regarded as incapable of regeneration. However, their ability to regenerate crucially depends on the location of the injury.

08.07.2020
15:51 FierceBiotech.comGilead axes $445M Precision Biosciences gene therapy hep B pact (4)

Gilead axes $445M Precision Biosciences gene therapy hep B pact badams Wed, 07/08/2020 - 08:28

10.07.2020
17:22 Nature.ComBlood from fit mice bestows brain benefits of exercise (3)

13:32 FightAging.OrgStem Cell Exhaustion in the Aging Lung (3)

Stem cell activity declines with age throughout the body. In some cases this is because stem cells become less active in response to changes in the signaling environment. In other cases, the cells are damaged or the populations greatly reduced. The consequence of this decline is that fewer daughter somatic cells are produced to make up losses, repair damage, and maintain tissue function. A slow decline into organ dysfunction results, contributing to the onset of age-related disease, disability, and mortality. Finding ways to reverse this process is a very important component of of the broader field of rejuvenation research. Tissue stem cell exhaustion is a key hallmark of aging, and in this study, we characterised its manifestation in the distal lung. We compared the lungs […]

07.07.2020
19:50 ScienceDaily.comCircular RNA makes fruit flies live longer (3)

The molecule influences the insulin signalling pathway and thus prolongs life.

19:28 Phys.orgScientists use nanoparticle-delivered gene therapy to inhibit blinding eye disease in rodents (3)

In experiments in rats and mice, two Johns Hopkins scientists—an engineer and an ophthalmologist—report the successful use of nanoparticles to deliver gene therapy for blinding eye disease. A uniquely engineered large molecule allows researchers to compact large bundles of therapeutic DNA to be delivered into the cells of the eye.

19:15 Phys.orgRNA key in helping stem cells know what to become (3)

Look deep inside our cells, and you'll find that each has an identical genome -a complete set of genes that provides the instructions for our cells' form and function.

18:48 Zdnet.comFrom open source to AI, tech is changing everything about the future of medicine (3)

The coronavirus pandemic has caused significant shifts in how healthcare is delivered. How many of these advances will last beyond the virus?

02:45 News-Medical.NetFlorida man infected with brain-eating amoeba (3)

The health agency announced that one patient in Hillsborough County contracted the Negleria fowleri, a water-borne and single-cell amoeba that targets the brain. The amoeba can cause a rare infection of the brain known as primary amebic meningoencephalitis (PAM), which destroys brain tissue.

13.07.2020
12:22 Technology.orgDissecting fruit flies’ response to life-extension diet (2)

Changes in a few small molecules involved in a cell’s metabolism seem to indicate whether a restricted “life

11.07.2020
16:56 Technology.orgBrd2 Inhibition as an Approach to Slow Aging (2)

There are innumerable studies showing small gains in mouse life span. Most cannot be reproduced, particularly the older

09.07.2020
21:08 Phys.orgSafer CRISPR gene editing with fewer off-target hits (2)

The CRISPR system is a powerful tool for the targeted editing of genomes, with significant therapeutic potential, but runs the risk of inappropriately editing "off-target" sites. However, a new study publishing July 9, 2020 in the open-access journal PLOS Biology by Feng Gu of Wenzhou Medical University, China, and colleagues, shows that mutating the enzyme at the heart of the CRISPR gene editing system can improve its fidelity. The results may provide a therapeutically safer strategy for gene editing than using the unmodified enzyme system.

12:48 NYT ScienceJapan’s Deadly Combination: Climate Change and an Aging Society (2)

Record-breaking rains this week in the country’s southernmost main island, which have killed 62, have shown the vulnerability of people living in nursing homes.

08.07.2020
16:04 News-Medical.NetHorizon Discovery introduces Cas9 and dCas9-VPR stable cell lines to simplify and accelerate CRISPR gene editing workflows (2)

Horizon Discovery Group plc, today announced the introduction of its stably expressing Cas9 and dCas9-VPR cell lines to help accelerate gene knockout.

04:30 News-Medical.NetScientists receive grant to study cerebrovascular changes during healthy and Alzheimer's aging (2)

Scientists often focus on abnormal accumulations of proteins called plaques in the brain in efforts to find a treatment for Alzheimer's disease. But the effects of these plaques have not been clear.

03:36 News-Medical.NetNew 'catch and kill' air filter can trap SARS-CoV-2 virus (2)

Researchers from the University of Houston, in collaboration with others, have designed a "catch and kill" air filter that can trap the virus responsible for COVID-19, killing it instantly.

02:17 ScienceMag.orgHummingbirds can count their way to food (2)

Tiny flyers show a concept of "numerical order" rarely seen in the wild

01:24 News-Medical.NetUnique photonic device could pave the way for a breakthrough in medical implants (2)

Over the past few decades, medical technology seen various advances in terms of the scope and efficiency of implant devices.

00:45 Drugs.comHealthier School Meal Programs Helped Poorer Kids Beat Obesity: Study (2)

TUESDAY, July 7, 2020 -- Just how healthy has the introduction of healthier new meals at America's schools been for kids? A new study ties the policy move to about a half-million fewer obese U.S. children. The study covered kids aged 10 to 17. It...

07.07.2020
22:24 FightAging.OrgBrd2 Inhibition as an Approach to Slow Aging (2)

There are innumerable studies showing small gains in mouse life span. Most cannot be reproduced, particularly the older ones, those that took place before it was common knowledge in the research community that one has to very aggressively control for accidental calorie restriction. If an intervention makes mice eat less, then they will tend to live longer, even if the intervention is modestly toxic. The improvements to health and longevity produced by calorie restriction in short-lived species are larger than near all other interventions assessed to date. Nonetheless, mechanisms that reliably (and usually modestly) slow aging in short-lived species do exist, acting to adjust metabolism into a more favorable state. Many are connected to calorie restriction, in which stress response processes are upregulated, and are […]

17:51 News-Medical.NetNew web-based tool could contribute to the development of better cancer treatments (2)

The results are now published in Nature Medicine and at the same time the tool - the Molecular Tumor Board Portal - will be launched on www.mtbp.org. Janne Lehtiö, professor at the Karolinska Institutet Department of Oncology-Pathology led this work, along with researcher David Tamborero.

17:36 News-Medical.NetResearchers use nanoparticles to deliver gene therapy for blinding eye disease (2)

In experiments in rats and mice, two Johns Hopkins scientists -; an engineer and an ophthalmologist -; report the successful use of nanoparticles to deliver gene therapy for blinding eye disease.

17:26 Drugs.comAs REM Sleep Declines, Life Span Suffers (2)

TUESDAY, July 7, 2020 -- Deep sleep is essential for good health, and too little of it may shorten your life, a new study suggests. REM (rapid eye movement) sleep is when dreams occur and the body repairs itself from the ravages of the day. For...

17:22 News-Medical.NetStudy: Animal proteins are more effective than plant proteins in building aging muscles (2)

On a gram for gram basis, animal proteins are more effective than plant proteins in supporting the maintenance of skeletal muscle mass with advancing age, shows research presented this week at The Physiological Society's virtual early career conference Future Physiology 2020.

05:23 News-Medical.NetTargeted deep brain stimulation may improve treatment of obsessive-compulsive disorder (2)

A group of researchers from Charité - Universitätsmedizin Berlin have further refined the use of deep brain stimulation in the treatment of obsessive-compulsive disorder.

03:14 Technology.orgNew gel could heal corneas and reduce the need for transplant (2)

Medical science is incredibly advanced, but there are still so many problems. For example, we can know replace

02:19 News-Medical.NetResearchers identify immune cell that predicts transplant patient's risk of organ rejection (2)

Researchers at The Ohio State University College of Medicine are the first to identify an immune cell that may predict a transplant patient's risk of developing antibodies that can cause organ rejection.

13.07.2020
15:59 FierceBiotech.comRoche targets 2021 start for hemophilia A gene therapy phase 3 as optimization effort drags on (1)

Roche targets 2021 start for hemophilia A gene therapy phase 3 as optimization effort drags on ntaylor Mon, 07/13/2020 - 08:35

15:31 News-Medical.NetBreakthrough discovery could lead to ‘kinder’ treatments for childhood bone cancer (1)

Researchers at the University of East Anglia and University of Manchester have made an important breakthrough that could lead to ‘kinder’ treatments for children with bone cancer, and save lives.

09:24 BBC Health'Breakthrough' cancer study adds to Super Strong Sophie's legacy (1)

The father of a five-year-old who died from cancer says he is proud she could help researchers.

11.07.2020
19:56 ScienceDaily.comStudy pinpoints brain cells that trigger sugar cravings and consumption (1)

New research has identified for the first time the specific brain cells that control how much sugar you eat and how much you crave sweet tasting food. The study specifically identifies the brain cells that respond to the hormone FGF21 to regulate sugar intake and sweet taste preference.

10.07.2020
23:34 DigitalTrends.comTech Briefs: Samsung’s 5G, food delivery consolidation, Disney+ (1)

'The Hamilton Effect' has been a boon for Disney's streaming service

22:37 FightAging.OrgIt is Challenging to Find Support for Evolutionary Trade-offs Between Reproduction and Aging in Human Data (1)

The disposibility theory of aging is one of numerous evolutionary theories of aging that seek to explain why aging exists and is near universal across species. In this case, aging is viewed as the inevitable result of trade-offs between resources allocated to reproduction versus resources allocated to tissue maintenance. Like near all evolutionary theories, and particularly those relating to aging, the models and the science are much debated. Since there is some variation between individuals within a species, one should expect to find a distribution of outcomes for any given trade-off when comparing large numbers of individuals of a given species. In this case, for this view of the origin of aging, we should expect to see that greater reproductive success correlates with a worse […]

19:39 ScienceDaily.comChanges in the immune system can promote healthy aging (1)

As we age, the immune system gradually becomes impaired. One aspect of this impairment is chronic inflammation in the elderly, which means that the immune system is constantly active and sends out inflammatory substances. Such chronic inflammation is associated with multiple age-related diseases including arthritis and Alzheimer's disease, and impaired immune responses to infection. One of the questions in ageing research is whether chronic inflammation is a cause of aging, or a consequence of the aging process itself? Scientists have found evidence suggesting that increased inflammation causes the aging process to speed up, and that there is a fine balance between maintaining immune system function and longevity.

18:14 Phys.orgDiscovery of a novel drug candidate to develop effective treatments for brain disorders (1)

Researchers at IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) have discovered a novel chemical compound that has the potential to become a new drug for the treatment of core symptoms of brain disorders like Down syndrome and autism. These results were obtained in preclinical models where the new compound ameliorated difficulties in cognitive tasks, as well as social interactions and repetitive behaviors present in neurodevelopmental and possibly neurological disorders. The study has been published in the scientific journal Chem.

16:40 Technology.orgThe Aging Gut Microbiome Produces More Trimethylamine, Harming Arterial Function (1)

In recent years academic interest has grown in the study of the gut microbiome. Researchers are making inroads

16:09 Phys.orgCause of oversized placentas in cloning found after two decades (1)

One reason a technique for cloning animals often results in oversized placentas, and hence failed births, has been uncovered in mice by an all-RIKEN team. This finding will help improve the success rate of the cloning method and could also shed light on fertility treatments for people.

15:54 Zdnet.comElon Musk: Update to Neuralink computer-brain tech is coming soon (1)

"Dire brain injuries" are Neuralink's first priority, says Elon Musk.

15:38 Phys.orgScientists discover extraordinary regeneration of neurons (1)

Biologists from the University of Bayreuth have discovered a uniquely rapid form of regeneration in injured neurons and their function in the central nervous system of zebrafish. They studies the Mauthner cells, which are solely responsible for the escape behavior of the fish, and previously regarded as incapable of regeneration. However, their ability to regenerate crucially depends on the location of the injury. In central nervous systems of other animal species, such a comprehensive regeneration of neurons has not yet been proven beyond doubt. The scientists report their findings in the journal Communications Biology.

14:05 Phys.orgThe next trend in food: Edible insects? (1)

You might not have known, but a lot of people think you should be eating insects. Their arguments are legion: Edible bugs are better for the environment and can help slow climate change, they can alleviate malnutrition and ease food insecurity. Also, they're delicious.

09:25 AzoRobotics.comTELUS and Zebra Medical Vision to Improve AI-Based Preventative Care in Canada (1)

Zebra Medical Vision (https://www.zebra-med.com/), the deep-learning medical imaging analytics company, announced today it has entered a strategic collaboration with TELUS Ventures, one of...

09:25 AzoRobotics.comArctoris and Insilico Medicine to Integrate AI and Robotics for COVID-19 (1)

Insilico Medicine, a biotechnology company developing an end-to-end drug discovery pipeline utilizing next-generation artificial intelligence, today announced a technology partnership with Arctoris,...

09.07.2020
18:00 News-Medical.NetStudy shows optimistic people sleep better and live longer (1)

Optimists live longer than pessimists and have a lower risk of chronic disease - this has been scientifically validated on multiple occasions.

10:46 Phys.orgExtreme rainfall events cause top-heavy aquatic food webs (1)

An expansive, multi-site ecology study led by UBC has uncovered new insights into the effects of climate change on the delicate food webs of the neotropics.

08.07.2020
19:32 NewScientist.ComThe powerhouses inside cells have been gene-edited for the first time (1)

Making precise changes to the genomes of mitochondria within our cells could lead to treatments for disorders that can result in muscle weakness or even death in early childhood

18:33 Nature.ComA bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing (1)

02:56 News-Medical.NetCerebrospinal fluid autoantibodies target the brain in some COVID-19 patients (1)

A study conducted by German researchers has shown that the neurological symptoms observed in some patients with coronavirus disease 2019 (COVID-19) may be caused by autoantibodies targeting the brain.