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15:07 CNBC health carePfizer buys stake in French gene therapy firm Vivet (4)

Pfizer Inc said on Wednesday it has acquired a 15 percent stake in Vivet Therapeutics, and has an exclusive option to fully acquire the privately held French company that develops gene therapies for liver disorders.

09:15 Google news Sci/TechWorld Health Organization panel weighs in on CRISPR-babies debate - (4)

    World Health Organization panel weighs in on CRISPR-babies debate  Nature.comWorld Health Organization calls for strong gene editing framework  AxiosW.H.O. Panel Demands a Registry for Human Gene Editing  The New York TimesWHO advisers call for registry of studies on human genome editing  STATWHO declares gene editing babies is 'irresponsible' but stops short of a ban  Daily MailView full coverage on Google News

02:12 Google news Sci/TechWorld Health Organization calls for strong gene editing framework - Axios (4)

    World Health Organization calls for strong gene editing framework  AxiosWHO advisers call for registry of studies on human genome editing  STATWHO expert panel paves way for strong international governance on human genome editing  World Health OrganizationView full coverage on Google News

23:03 ScienceWHO panel calls for registry of all human gene editing research (4)

It would be irresponsible for any scientist to conduct human gene-editing studies in people, and a central registry of research plans should be set up to ensure transparency, World Health Organization experts said on Tuesday.

18:10 Phys.orgCRISPR gene editing: Why we need Slow Science (4)

In a newly published article in Nature, a group of prominent scientists and ethicists have called for a moratorium on clinical research using CRISPR/Cas9 gene editing.

16:37 FierceBiotech.comBiogen-Nightstar deal sheds light on gene therapy feeding frenzy (4)

The level of interest in gene therapies has been laid bare by a report on Biogen’s pursuit of Nightstar Therapeutics. Biogen ultimately landed its target with an $877 million (€772 million) all-cash offer, but only after seeing off interest from three other companies.

23:38 TechInvestorNews.comSilicon Valley techies are turning to a cheap diabetes drug to help them live longer (CNBC: Top News) (3)

CNBC: Top NewsSilicon Valley techies are turning to a cheap diabetes drug to help them live longer - Doctors feel that taking metformin is mostly safe, but cautioned about the lack of clinical studies. ...

21:44 ScienceDaily.comDiscovery may lead to precision-based strategy for triple negative breast cancer (3)

A researcher in the Vera Bradley Foundation Center for Breast Cancer Research at the Indiana University School of Medicine, working in collaboration with researchers from the University of Maryland, recently reported several important findings related to triple negative breast cancer and its future treatment in the journal Nature Nanotechnology.

04:05 Gizmag WHO calls for global gene editing research registry as debate over moratorium rages (2)

Following on from a recent call for a global moratorium on human germline gene editing, several scientists have pushed back against the idea, suggesting blanket prohibition is both redundant and problematic. The World Health Organization's advisory panel on the topic also sidestepped the issue of a moratorium, instead recommending a central registry on human genome editing research be created.
.. Continue Reading WHO calls for global gene editing research registry as debate over moratorium rages Category: Science Tags: CRISPR ethics Genetics Genome World Health Organization

17:37 TechInvestorNews.comStar Wars: The Clone Wars leaving Netflix in April - CNET (Sean Keane/CNET - Business Tech) (2)

Sean Keane / CNET - Business TechStar Wars: The Clone Wars leaving Netflix in April - CNET - Get your binge in before Netflix executes Order 66. ...

13:59 Technology.orgGene Therapy Shows Initial Promise for Parkinson’s Disease (2)

A delicate operation that involved placing a gene into the brain was found to reduce the severity of

13:59 Phys.orgNot all stem cells are created equal, study reveals (2)

Researchers from the University of Toronto's Institute for Biomaterials and Biomedical Engineering (IBBME) and the Donnelly Centre have discovered a population of cells – dubbed to be "elite" – that play a key role in the process of transforming differentiated cells into stem cells. The finding has important implications for regenerative medicine.

10:21 News-Medical.NetLian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes (2)

Xiaojun "Lance" Lian, assistant professor of biomedical engineering, was one of three recipients of the College of Engineering's ENGineering for Innovation & Entrepreneurship grant for "Small Molecule-Based Definitive Endoderm Kit and Pancreatic Progenitor Kit for Stem Cell Research and Therapy."

09:14 News-Medical.NetNanofibrous membrane could enhance periodontal tissue regeneration (2)

According to the U.S. Centers for Disease Control and Prevention, about half of all Americans will have periodontal disease at some point in their lives.

21:11 Nature.ComBaby monkey is first primate created using sperm from tissue transplanted into dad (2)

18:01 Phys.orgUsing more-specific 'genetic scissors' may avoid problems associated with gene editing (2)

Recent studies have suggested a potential barrier to making CRISPR gene-editing treatments a viable option for inherited blood-related disorders such as sickle cell anemia, thalassemia, and primary immunodeficiency syndromes. Stem cells may respond to having their genes edited by shutting down—and trying to get around this roadblock could increase the risk of cancer.

23:31 Washingtonpost Speaking-of-scienceNIH and top scientists call for moratorium on gene-edited babies (2)

Researchers are alarmed by “rogue human experimentation” using CRISPR in China.

21:13 News-Medical.NetCRISPR/Cas libraries could revolutionize drug discovery (2)

CRISPR/Cas enables the targeted deactivation of genes by cutting DNA at pre-determined sites. This is accomplished by providing the Cas enzyme with a genetic zip code.

18:53 News-Medical.NetGene editing and designer babies experiments face global moratorium (2)

Powerful gene editing tools could soon face a global regulations on their use on human embryos, sperms or eggs.

17:56 Google news Sci/TechBeto O'Rourke ate dirt with 'regenerative powers' after losing to Ted Cruz: report - Fox News (2)

    Beto O'Rourke ate dirt with 'regenerative powers' after losing to Ted Cruz: report  Fox NewsAre Beto and Amy O'Rourke the future of politics or the past?  The Washington PostBeto O'Rourke in 2012 said the US had an 'extravagant government' that needed 'significant' spending cuts  CNNIs Betomania Real or Phony?  The New York TimesNewt Gingrich: Beto O'Rourke and 2020: I made a lot of assumptions about the candidate and I was wrong  Fox NewsView full coverage on Google News

16:57 FierceBiotech.comWHO panel pushes for genome editing research registry (2)

A WHO advisory committee has spoken out against clinical applications of human germline genome editing. The panel, which formed in the wake of China’s germline modification scandal, wants WHO to create a central registry on human genome editing research as part of an effort to boost global governance of the field.

16:45 FierceBiotech.comPfizer eyes Fierce 15 winner Vivet buy as gene therapy fever heats up (2)

Vivet is in the crosshairs of Big Pharma Pfizer as the U.S. giant looks to get in on the new industry craze of buying up small gene therapy biotechs.

15:32 Technology.orgUW team finds key to common cancer pathway in discovery that could unlock new therapies (2)

Scientists have long known that the protein p53, when mutated, is a critical factor in the onset of

01:37 Nanowerk.comNew nanomaterial will allow abandoning bone marrow transplantation (2)

Scientists have developed a nanomaterial, which will be able to restore the internal structure of bones damaged due to osteoporosis and osteomyelitis. A special bioactive coating of the material helped to increase the rate of division of bone cells by 3 times.

00:20 ScienceMag.orgWHO panel proposes new global registry for all CRISPR human experiments (2)

The World Health Organization should also step up governance of human genome-editing research, group says

00:04 ScienceDaily.comFountain of youth for heart health may lie in the gut (2)

As our collection of resident gut bacteria changes with age, it increasingly produces harmful metabolites that damage veins and blood vessels, driving disease, a new study suggests.

23:14 HealthWHO panel calls for registry of all human gene editing research (2)

It would be irresponsible for any scientist to conduct human gene-editing studies in people, and a central registry of research plans should be set up to ensure transparency, World Health Organization experts said on Tuesday.

19:06 Rejuvenation ResearchGlycolytic Inhibitor 2-Deoxy-D-Glucose at Chronic Low Dose Mimics Calorie Restriction in Rats Through Mitohormetic Induction of Reactive Oxygen Species (2)

Rejuvenation Research, Ahead of Print.

19:06 Rejuvenation ResearchValidated Living Worldwide Supercentenarians 112+, Living and Recently Deceased: February 2019 (2)

Rejuvenation Research, Volume 22, Issue 1, Page 79-81, February 2019.

19:06 Rejuvenation ResearchStem Cell-Induced Pulp Regeneration Can Be Enhanced by Administration of CCL11-Neutralizing Antibody in the Ectopic Tooth Transplantation Model in the Aged Mice (2)

Rejuvenation Research, Volume 22, Issue 1, Page 51-59, February 2019.

16:02 Phys.orgBiologists develop new method of cloning (2)

DNA, which contains the genetic information of an organism, consists of long chains of nucleotides. In order to study the functions based on the sequence of these building blocks, DNA molecules must be inserted in carrier molecules (plasmid-vectors) to be multiplied. For this cloning process, a research team from the University of Bayreuth has developed a highly efficient, fast and inexpensive method that is versatile enough to be deployed in all areas of biology, biochemistry and biotechnology. A key feature of the method is that it makes any painstaking screening of bacterial colonies unnecessary. The scientists presented their innovation in the journal Scientific Reports.

15:26 Phys.orgGet ready for a menu of lab-grown steaks, "bleeding" plant burgers, and cricket smoothies (2)

It takes about 90 seconds of flipping and stirring for Josh Hyman to whip up a skillet of fluffy, pale yellow scrambled eggs. He's in an industrial kitchen in San Francisco, and I'm 3,000 miles away on my farm in rural Tennessee, watching Hyman cook via Skype. He tips the craggy yellow mounds out of the pan and onto the plate, the eggs jiggling as they slide.

14:52 AzoRobotics.comUvA Professors Launch AI Research Lab to Use AI for Medical Image Analysis (2)

Cees Snoek and Marcel Worring, UvA professors, are launching a new public-private research lab in collaboration with scientists from the Inception Institute of Artificial Intelligence Ltd. from the...

11:43 AzoRobotics.comSilicon Valley-Based Food Robotics Company Expands Health Facility Footprint (2)

Silicon Valley-based food robotics company Chowbotics created Sally the Robot to serve nutritious food anytime, anywhere. By partnering with Chowbotics to bring Sally on campus, hospitals around the...

19:08 Phys.orgNew CRISPR-powered device detects genetic mutations in minutes (1)

A team of engineers at the University of California, Berkeley and the Keck Graduate Institute (KGI) of The Claremont Colleges combined CRISPR with electronic transistors made from graphene to create a new hand-held device that can detect specific genetic mutations in a matter of minutes.

16:23 Editors' SuggestionsPattern formation of skin cancers: Effects of cancer proliferation and hydrodynamic interactions (1)

Author(s): Takuma Hoshino, Ming-Wei Liu, Kuo-An Wu, Hsuan-Yi Chen, Tatsuaki Tsuruyama, and Shigeyuki KomuraSkin tumors can exhibit characteristic patterns that may help in diagnosing them. The authors use a phase-separation model with hydrodynamic effects to understand the formation of these patterns. A simulation that includes a growth term and a friction term is able to reproduce some of the clinically observed patterns.
[Phys. Rev. E 99, 032416] Published Thu Mar 21, 2019

15:08 FierceBiotech.comCelgene taps Exscientia’s AI drug discovery tech for 3 new programs (1)

Exscientia is adding another Big Pharma to its list of partners. This time, the drug discovery specialist is teaming up with Celgene on three programs in oncology and autoimmunity.

05:45 ScienceDaily.comPotential new combination treatment for pancreatic cancer (1)

Researchers have identified a possible new therapeutic strategy using two types of drug inhibitors at once to treat one of the world's deadliest cancers.

04:34 BusinessDrink hot tea at your own risk: New study is latest to show link to esophageal cancer (1)

23:40 NYT ScienceChop Up a Worm. It Will Regenerate. Scientists Figured Out Why. (1)

Researchers identified the master control gene that enables worms to grow a new body, capturing the imagination of some humans looking for a fresh start.

21:24 ReutersU.S. jury hears more evidence as second phase of Roundup cancer trial begins (1)

A lawyer for a man who sued Bayer AG unit Monsanto after developing cancer on Wednesday told a jury about the company's alleged efforts to influence scientists and regulators, a day after the jury found Bayer's glyphosate-based weed killer Roundup to have caused the man's disease.

19:45 Yahoo ScienceThe Psychology Behind People Who Fake Cancer (1)

"That was a spectacularly rare case," said Marc Feldman, a psychiatrist whospecializes in factitious disorders and the author of Dying to Be Ill

19:22 Yahoo SciencePfizer/Merck KGaA End Bavencio+Talzenna Ovarian Cancer Study (1)

Pfizer (PFE) and Merck KGaA terminate a late-stage study on Bavencio and its new PARP inhibitor, Talzenna. This is the third ovarian cancer study failure in less than six months.

19:22 BusinessPfizer/Merck KGaA End Bavencio+Talzenna Ovarian Cancer Study (1)

Pfizer (PFE) and Merck KGaA terminate a late-stage study on Bavencio and its new PARP inhibitor, Talzenna. This is the third ovarian cancer study failure in less than six months.

18:35 Yahoo ScienceHancock accused of astonishing ignorance after he speaks about his prostate cancer risk (1)

Matt Hancock has been accused of “an astonishing level of ignorance” after revealing that tests had found he is at increased risk of prostate cancer.   One leading geneticist said the Health Secretary had “massively misinterpreted” his results, and would be wasting NHS resources by booking an appointment to discuss the matter with his GP.   Mr Hancock revealed the results of his genetic tests as he called for the health service to roll out gene tests more widely. But scientists today criticised the drive, with Mr Hancock accused of making “frankly ridiculous” claims, in his speech to The Royal Society. Meanwhile GPs said encouraging people to routinely be tested for common diseases would uncover too many “unimportant” findings which would leave patients needlessly distressed, while heaping pressure on surgeries.   The facts | Prostate cancer Mr Hancock said the tests found he has a 15 per cent chance of suffering prostate cancer by the age of 75 - around 50 per cent higher than average. The Health Secretary, 40, said the news had left him worried, saying he would now be seeking a blood test from his GP, and ensuring he did not miss any screening appointments. He also said he would make sure he did not miss any screening appointments. The NHS normally only provides PSA blood tests - which can show an increased risk of prostate cancer - from the age of 50, if requested, or from the age of 45 when there is a family history of disease. There is no NHS screening programme for prostate cancer. Today  Professor David Curtis, UCL Genetics Institute & Barts and the London School of Medicine and Dentistry, said the Health Secretary had “massively misinterpreted the meaning of the score he has been given.” He said Mr Hancock’s score would not be considered high risk, and that the difference between it and average risk could come down to a “margin of error”. Prof Curtis said the Health Secretary would waste scarce resources by booking a “completely unnecessary appointment with his GP to discuss a course of action to address a problem which essentially does not exist.” prostate cancer cases And he said other comments by Mr Hancock displayed “a quite astonishing level of ignorance about the NHS.” “He says he is going to make certain that he does not miss any screening appointments. That should be easy, because there is no such thing as a screening appointment for prostate cancer. We don’t do them because they don’t work, they’re a waste of time and money, they cause unnecessary anxiety to patients and unnecessary work for health professionals.” In a lengthy tirade, the geneticist said: “His claim that this test may have saved his life is frankly ridiculous. It really demonstrates an astonishing and worrying degree of innumeracy and lack of comprehension of health issues.” Professor Helen Stokes-Lampard, Chairman of the Royal College of GPs, urged ministers to be cautious in the rollout of gene testing. She said: “Genomic research will have an increasingly important place in shaping the care we are able to provide to patients in the NHS and advances in medical research must be properly evaluated to ensure that they do benefit patients. But we also need to ensure that genomic data is used responsibly, ethically, and in a way that does not increase pressure on the NHS without the appropriate mitigating measures in place to cope with it. “Many things that will be picked up by genetic testing will be unimportant or of dubious value, and these could leave people unnecessarily confused and distressed. This will undoubtedly lead to an increased number of worried people wanting to visit their GP to discuss their borderline results, at a time when general practice is already struggling to cope with intense demand – and millions of patients are already waiting too long for an appointment,” he said. In the speech today, Mr Hancock said too much data was “locked away” in research labs, as a result of bureaucratic obstacles and scientists refusing to share it. Currently the NHS offers limited gene testing, when patients are thought to be at higher risk because of a family history of disease. The Government has set out an ambition to sequence 5 million genomes over the next five years to build a diagnostic, predictive, preventive and personalised health and care service. So far 100,000 genomes have been sequenced, allowing one in four participants with rare diseases receiving a diagnosis for the first time. Vivienne Parry, head of engagement at Genomics England, said: “Our current focus is those with rare disease or cancer and we are only just beginning to think about risk scoring for healthy people which will need a great deal of work before it is ready for widespread NHS use. "

18:35 BusinessGlaxo Presents Encouraging Data on Endometrial Cancer Drug (1)

Glaxo (GSK) presents encouraging data from phase I/II study on endometrial cancer drug, dostarlimab.

18:30 Financial TimesGoFundMe blocks appeals for controversial cancer clinic (1)

Crowdfunders face scrutiny over unproven medical treatments

18:04 ScienceDaily.comActive substance from plant slows down aggressive eye cancer (1)

An active substance that has been known for 30 years could unexpectedly turn into a ray of hope against eye tumors. This is shown by a new study. The plant leaves of which contain the tested substance is anything but rare: At Christmas time you can find it in every well-assorted garden center.

17:57 TechnologyGoFundMe blocks appeals for controversial cancer clinic (1)

Crowdfunders face scrutiny over unproven medical treatments