Minuscule lab-grown models of human brains can be fitted with caps that measure their activity, just as electroencephalogram (EEG) caps record electrical signals produced by full-size human brains. The minibrains are examples of organoids—three-dimensional clusters of living cells, grown in a lab, that simulate the structure and function of human organs so that researchers can…

DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived

Less can be more in caring for the post-100 set.

Inventia Life Science and Xylyx Bio today announced their strategic partnership following promising results developing more realistic, scalable, and reproducible 3D cell cultures for drug discovery and biomedical research.

Deep molecular analysis of the bone marrow microenvironment reveals that the cells regulating blood stem cell maintenance are more diverse than expected and have features likely to be conserved between species.

Do pediatric kidney transplant patients have better long-term outcomes when their kidney comes from living, biologically unrelated donors compared to deceased donors?

A new report on lung transplantation success rates confirms that Cedars-Sinai patients experienced one-year survival outcomes of 91.49%, an achievement above the national average of 89.46%.

Research with stem cells is becoming increasingly important, because stem cells can develop into any body cell—skin cells, nerve cells or organ cells such as liver cells, the so-called hepatocytes. Stem cells can therefore be used, for example, in therapy for organ damage or as an alternative to animal experiments.

Ileana Piña speaks with Bart Griffith about the first porcine-to-human cardiac xenotransplantation and where the field is going.

Thank you for joining us on “The cloud hub: From cloud chaos to clarity.” Health care organizations have many emerging opportunities to apply artificial intelligence in new ways. To do it right, AI in health care should always begin with a patient-centered approach. Click here to continue.

Many BAME patients waiting for a donor kidney are blood type B so development could be 'game-changer'

Habitual coffee consumption may lower your risk of heart disease and death in a given time period, but the jury is still out on whether it promotes longevity.

For the first time, researchers can get a high-resolution view of single blood stem cells thanks to a

California proposes to extend life of last nuclear plant at cost of $1.4 billion  POLITICOCalifornia Gov. Gavin Newsom looks to extend life of state's last operating nuclear power plant  Fox NewsNuke or no nuke? California officials ponder nuclear future  KRCRCalifornia governor proposes $1.4 billion loan to keep nuclear plant open  ReutersView Full Coverage on Google News

California proposes to extend life of last nuclear plant at cost of $1.4 billion  POLITICOCalifornia Gov. Gavin Newsom looks to extend life of state's last operating nuclear power plant  Fox NewsNuke or no nuke? California officials ponder nuclear future  The Associated PressCalifornia governor proposes $1.4 billion loan to keep nuclear plant open  Reuters

California Gov. Gavin Newsom looks to extend life of state's last operating nuclear power plant  Fox NewsCalifornia governor proposes $1.4 billion loan to keep nuclear plant open  ReutersNuke or no nuke? California officials ponder nuclear future  The Associated PressCalifornia would loan PG&E $1.4 billion to keep nuclear plant open under Newsom proposal  Sacramento Bee

California Gov. Gavin Newsom looks to extend life of state's last operating nuclear power plant  Fox NewsCalifornia governor proposes $1.4 billion loan to keep nuclear plant open  ReutersNuke or no nuke? California officials ponder nuclear future  The Associated PressCalifornia would loan PG&E $1.4 billion to keep nuclear plant open under Newsom proposal  Sacramento BeeView Full Coverage on Google News

Law.comScott Grahamhttps://images.law.com/contrib/content/uploads/sites/292/2022/08/Wolf-Matthew-M-767x633.jpgSkilled in the Art/Biotechnology/Health Care/Technology Media and Telecom/News/California/Minneapolis/Texas/Washington, DC Metro/Intellectual Pro / Law.comSkilled in the Art With Scott Graham: Hologic Comes From Behind to Win on Assignor Estoppel + Juror - Minerva Surgical won a Supreme Court decision last year narrowing the doctrine of assignor estoppel, but it wasnt enough to unwind a $5 million jury verdict at CAFC. ...

A research team led by Professor Park Sang-Hyun of the Department of Robotics and Mechatronics Engineering (also in charge of the Artificial Intelligence major) at DGIST (President Kuk Yang) developed a weakly supervised deep learning model that can accurately show the presence and location of cancer in pathological images based only on data where the cancer is present. Existing deep learning models needed to construct a dataset, in which the location of the cancer was accurately drawn, to specify the cancer site.

OsteoApp.ai, Inc., ("OsteoApp.ai") an emerging AI driven healthcare company focused on bone strength and fracture risk assessments using standard digital x-rays, announces a multi-center...

Jesse Hollington / Digital TrendsOppo’s latest Apple Watch clone has an important spec under the hood - Oppo has just announced the first smartwatches with Qualcomms new Snapdragon W5 Gen 1 chip and a fascinating new design. ...

Genome editing can cure diseases, boost food production and open vast new fields of scientific discovery. But to realize its full potential, scientists need to precisely describe the details of their genome editing attempts to one another and the wider world.

DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential for confirming if cell lines are usable.

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

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The performance of workers across their employment life span has been mapped by a new study, which found that more complex jobs can help employees to maintain their ability to be proactive and adaptive at work as they grow older.

Female white-faced capuchin monkeys living in the tropical dry forests of northwestern Costa Rica may have figured out the secret to a longer life—having fellow females as friends.

A whole-body perfusion system restored cellular activity in pigs an hour postmortem

Fecal transplants have become a common procedure to treat bowel infections – but how do they work and are there any risks involved?

For the purpose of personalised therapies, researchers have used 3D printing to develop tablets based on different types of starch, and has confirmed that drug release could be tailored by optimising the right starch type and tablet shape.

Scientists have identify critical spots on the genome where gene editing could cause an unwanted response, and they provide recommendations for safer approaches.

CRISPR/Cas9 is a commonly used, very precise, gene editing technique whose development, by Jennifer A. Doudna and Emmanuelle Charpentier, was recognised with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors", CRISPR allows the introduction of the desired DNA sequence into (virtually) any spot of the genome, thus modifying or inactivating a gene. This technique is widely used in biomedical research and some CRISPR-based therapies are in clinical trials for the treatment of human blood disorders, some types of cancer and HIV, among other conditions.

For the first time, researchers can get a high-resolution view of single blood stem cells thanks to a little help from microscopy and zebrafish.

CRISPR/Cas9 is a precise gene editing technique whose development by Jennifer A. Doudna and Emmanuelle Charpentier was recognized with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors," CRISPR allows the introduction of the desired DNA sequence into (virtually) any spot of the genome, thus modifying or inactivating a gene. This technique is widely used in biomedical research and some CRISPR-based therapies are in clinical trials for the treatment of human blood disorders, some types of cancer and HIV, among other conditions.

Cell membrane-coated nanoparticles, applied in targeted drug delivery strategies, combine the intrinsic advantages of synthetic nanoparticles and cell membranes. Although stem cell-based delivery...

Imagine if one day blood transfusions from strangers were not needed because they could be produced from cells that line your own blood vessels' cells.

Cold atmospheric plasma can affect cell adhesion with a significant role in stem cell adhesion. In a new study now published in Scientific Reports, Kobra Hajizadeh and a team of researchers in the departments of physics and plasma research at the Islamic Azhad University and the CNRS, France, studied the effect of plasma treatment on human bone marrow mesenchymal stem cell (HBMMSC) adhesion to understand cell differentiation and cell fate.

Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how

Researchers delve deeper into the structure of protein receptor crucial for cardiovascular health

Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases.

Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases. The protein is involved in helping cells use energy our bodies convert from food. Prior to the development of this 3D structure, researchers only had models and were unable to determine how these mutations contribute to disease. Mitochondrial diseases are a group of inherited conditions that affect 1 in 5,000 people and have very few treatments.

Orthopaedic surgeons at NHS Golden Jubilee have performed the first meniscal transplant on a patient in Scotland.

It’s sunburn season. Many of us have experienced the pain and peeling from unprotected sun exposure. Still, we

A new study published in the journal Science reveals a unique form of cell communication that controls muscle repair.

Pig to human heart transplants are the future. Are we ready for it?  The GuardianScientists Partially Revived Pig Organs An Hour After Death In 'Stunning' New Research  Forbes Breaking NewsYale researchers revive cells in dead pigs, shaking up what we know about dying  WLS-TVResearch in pigs shakes up what we know about dying  CNNCheating Death: Yale Scientists Restore Cell, Organ Function in Pigs After Death  SciTechDailyView Full Coverage on Google News

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the progressive loss of motor neurons in the

Engineers at the University of Nebraska-Lincoln have devised a robot that helps medical professionals conduct surgical procedures from afar. It might someday perform surgery in space. The post A Surgery Robot Will Board the ISS in 2024 appeared first on ExtremeTech.

The circadian clock entrains rhythmic patterns in behavioral and physiological processes to temporally coordinate systemic metabolism with the rising and setting of the sun. In previous investigation on human subjects, sphingomyelins (SMs) exhibited strong rhythmicity on an individual basis. However, the mechanistic connection between SM and circadian regulation remains unclear.

Scientists revived the cells of pigs an hour after death, a potential organ transplant breakthrough  Livescience.comScientists Partially Revived Pig Organs An Hour After Death In 'Stunning' New Research  Forbes Breaking NewsResearch in pigs shakes up what we know about dying  CNNAn hour after pigs' deaths, an artificial system restored cellular life  Science News MagazineHow Scientists Are Reviving Cells in Dead Pigs’ Organs  The New York TimesView Full Coverage on Google News

It's sunburn season. Many of us have experienced the pain and peeling that comes from unprotected time in the sun, but we may not focus on a remarkable and vital part of the process: the regeneration of skin as the damaged tissue is replaced with new.

Scientists revitalized cells in the bodies of dead pigs.

CRISPR gene editing has been used to try to prevent a genetic disorder in dogs for the first time, in this case a common condition called hip dysplasia

One streamer spent big on Immortal, and he's "won" the game. His prize: being too overpowered to play with anyone else.  The post Diablo Immortal Player Drops $100K, Becomes Too Powerful to Find a Match appeared first on ExtremeTech.

Could it be the healthiest diet in the world? Here are seven science-backed benefits of the Mediterranean diet

Without Egg, Sperm or Womb: Synthetic Embryo Models May Enable Growing Organs for Transplantation  SciTechDailySynthetic embryos grown from stem cells don't need sperm or eggs  New AtlasScientists Create Mouse Embryos From Stem Cells  NewsmaxWith innovative bioreactor as womb, mouse stem cells transform into organ-filled embryos  ScienceIsraeli scientists make model synthetic mouse embryo with stem cells  The Jerusalem PostView Full Coverage on Google News

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the progressive loss of motor neurons in the brain and spinal cord responsible for voluntary movements and muscle control.

Research team intends to to try same process with human stem cells

Unknown to passersby, a modest little creature with amazing abilities lives and breeds in the forests and paddy fields of Japan. Now, researchers from Japan have discovered how these amphibians' superpowers are unleashed.

A miniaturized robot invented by Nebraska Engineering Professor Shane Farritor may soon blast into space to test its skills.

Read CNN's Cloning Fast Facts and learn more about the process of creating a genetically identical copy of an original.

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Researchers evaluated the infectivity of two SARS-CoV-2 A lineage variants on human ocular tissues in vitro.

Motivation: Cancer is heterogeneous, affecting the precise approach to personalized treatment. Accurate subtyping can lead to better survival rates for cancer patients. High-throughput technologies provide multiple omics data for cancer subtyping. However, precise cancer subtyping remains challenging due to the large amount and high dimensionality of omics data. Results: This study proposed Subtype-Former, a deep learning method based on MLP and Transformer Block, to extract the low-dimensional representation of the multi-omics data. K-means and Consensus Clustering are also used to achieve accurate subtyping results. We compared Subtype-Former with the other state-of-the-art subtyping methods across the TCGA 10 cancer types. We found that Subtype-Former can perform better on the benchmark datasets of more than 5000 tumors based on the survival analysis. In addition, Subtype-Former also achieved outstanding results in pan-cancer subtyping, which can help analyze the commonalities and

Motivation: Cancer is heterogeneous, affecting the precise approach to personalized treatment. Accurate subtyping can lead to better survival rates for cancer patients. High-throughput technologies provide multiple omics data for cancer subtyping. However, precise cancer subtyping remains challenging due to the large amount and high dimensionality of omics data. Results: This study proposed Subtype-Former, a deep learning method based on MLP and Transformer Block, to extract the low-dimensional representation of the multi-omics data. K-means and Consensus Clustering are also used to achieve accurate subtyping results. We compared Subtype-Former with the other state-of-the-art subtyping methods across the TCGA 10 cancer types. We found that Subtype-Former can perform better on the benchmark datasets of more than 5000 tumors based on the survival analysis. In addition, Subtype-Former also achieved outstanding results in pan-cancer subtyping, which can help analyze the commonalities and

What if, in people with blinding retinal disorders, one could simply introduce into the retina healthy photoreceptor cells

Metastasis is the spread of cancer cells to distant sites in the body. Essentially, cancer cells from the

Rejuvenation Research, Ahead of Print.

The team in the Hematology Department at Henri Mondor AP-HP Hospital, coordinated by Dr. Christine Robin, and scientists from the Institut Pasteur (the Invasive Bacterial Infections Unit led by Professor Muhamed-Kheir Taha) recently studied protection against meningococcal infection in patients who had received hematopoietic stem cell transplantation.

JMIR Publications recently published "Digital Life Coaching During Stem Cell Transplantation: Development and Usability Study" in JMIR Formative Research which reported that the authors launched a single-arm pilot study to investigate the feasibility of patient engagement with digital life coaching (DLC) during this intensive period.

The DeepMind program AlphaFold has predicted the structures of almost all proteins known to science.

The European Union (EU) aims to be climate-neutral, with net-zero greenhouse gas (GHG) emissions, by 2050. Transforming the agricultural sector, which generates 11% (429 megatons of CO2-eq in 2019) of the EU's total GHG emissions, is vital, not only to mitigate climate change but also to guarantee food security in increasingly extreme environmental conditions. The EU's new common agricultural policy includes improvements in that regard but needs to be more ambitious. The Committee on Agriculture and Rural Development (AGRI) of the European Parliament therefore commissioned a report from experts to learn about the potential of the EU's agricultural soils to sequester carbon and how their capacity to do so can be increased.

Experts hope to permanently correct or silence the inherited genetic material that is involved.

An injectable cure for inherited heart muscle conditions that can kill young people in the prime of their lives could be available within a few years, after an international team of researchers were announced as the winners of the British Heart Foundation's Big Beat Challenge.

Published by the Journal of Radiology: Artificial Intelligence, a prospective observational study across 12 hospital systems from the University of Minnesota Medical School evaluated the real-time performance of an interpretable artificial intelligence (AI) model to detect COVID-19 from chest X-rays.

A new study presented today at the Society of NeuroInterventional Surgery's (SNIS) 19th Annual Meeting shows that artificial intelligence (AI) technology can identify when a patient is having a stroke caused by emergent large vessel occlusion (LVO), therefore making them a candidate for endovascular therapy (EVT).

Prize from British Heart Foundation will fund international team to move experimental therapies toward clinical trials

Physicians and researchers from UK HealthCare's Transplant Center and the University of Kentucky Markey Cancer Center conducted a study of patients over the age of 70 with a type of liver cancer called hepatocellular carcinoma (HCC) and how the outcomes of ablative treatments compare to liver transplants.

Researchers have developed an AI algorithm that accurately and quickly diagnoses idiopathic pulmonary fibrosis, a lung disease. The algorithm makes its diagnosis based only on information from non-invasive examinations, including lung images and medical information collected during daily medical care.

DeepMind's AlphaFold now contains structure of 200M proteins. What does that mean for drug R&D?  Endpoints NewsDeepMind uncovers structure of 200m proteins in scientific leap forward  The GuardianDeepMind found the structure of nearly every protein known to science  The VergeAlphaFold reveals the structure of the protein universe  DeepMindDeepMind AI Lab Releases 200 Million 3D Images of Proteins | Time  TIMEView Full Coverage on Google News

These are the stocks posting the largest moves in midday trading.

DeepMind and EMBL's European Bioinformatics Institute (EMBL-EBI) have made AI-powered predictions of the three-dimensional structures of nearly all cataloged proteins known to science freely and openly available to the scientific community, via the AlphaFold Protein Structure Database.

A new study from Tel Aviv University (TAU) identifies risks in using CRISPR therapeutics, the innovative, Nobel-prize-winning method that

During cell division, chromosomes are replicated into two copies—one for each daughter cell. These copies, called sister chromatids, are usually considered identical. In fact, it's the two pairs of sister chromatids that make up the symmetrical X shape usually shown when visualizing chromosomes.

DeepMind says its AlphaFold tool has successfully predicted the structure of nearly all proteins known to science. From today, the Alphabet-owned AI lab is offering its database of over 200 million proteins to anyone for free.  When DeepMind introduced AlphaFold in 2020, it took the science community by surprise. Scientists had spent decades trying to…

A first-of-its-kind study of 1,813 older women suggests that the accelerated biological aging of the body — epigenetic

Oldest patient yet cured of HIV after stem cell transplant: researchers  New York Post Fourth person 'cured' of HIV, but is a less risky cure in sight?  FRANCE 24 EnglishLongtime HIV patient is effectively cured after stem cell transplant  The Washington PostView Full Coverage on Google News

A Nagoya University research group has developed an AI algorithm that accurately and quickly diagnoses idiopathic pulmonary fibrosis, a lung disease. The algorithm makes its diagnosis based only on information from non-invasive examinations, including lung images and medical information collected during daily medical care.

Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and how science impacts upon all aspects of society and life.

A patient entered remission from cancer and HIV after a transplant.

Longtime HIV patient is effectively cured after stem cell transplant  The Washington PostHIV+ Heart Transplant; Small Watchman Leaks Risky; Breakthrough COVID and High BP  Medpage TodayHIV+ Man, Also Battling Cancer, "Cured" Of Both After Complex Procedure In US  NDTVView Full Coverage on Google News

Two years ago, prosthetics startup Unlimited Tomorrow launched TrueLimb, its next-generation bionic arm. Six years of research and development went into TrueLimb, and the technology has given hundreds of people in the US an affordable, non-invasive way to replace lost limbs. Now, a new initiative is taking TrueLimb to a part of the world where […]

People with loss of urinary control who used the Yoga of Immortals mobile app – a globally used app that combines specific yogic postures in the Sanatan tradition with breathing exercises, sound therapy and meditation – found significant improvement in the frequency and severity of urine leaks at four weeks of practice, according to a Rutgers study.

A new study identifies risks in the use of CRISPR therapeutics -- an innovative, Nobel-prize-winning method that involves cleaving and editing DNA, already employed for the treatment of conditions like cancer, liver and intestinal diseases, and genetic syndromes.

webmaster@theregister.co.uk (Paul Kunert) / The RegisterSo much for that reported $1b. IBM says Watson Health assets only fetched $230m - Unit was supposed to transform oncology but never turned a profit and ended up in hands of private equity IBM has confirmed that Francisco Partners paid several hundreds of millions of private equity for the healthcare data and analytics assets housed by Watson Health, a unit that was offloaded in ...

Designing a protein is a bit like making a cabinet. The first step is building the backbone that holds the protein together. But then comes the hard part: figuring out where to install hinges on the scaffold—that is, finding the best “hotspots”—to put on doors, shelves, and other attachments that ultimately make the cabinet fully […]

1,2-dichloropropane (1,2-DCP) is a solvent used in the printing industry. It was linked to cholangiocarcinoma in 2013, when

In this interview, we speak to Echo Pan, a Ph.D. student from North Carolina State University about her latest research that used CRISPR to uncover more on probiotics.

Artificial Intelligence is being increasingly incorporated within rapid diagnostic test kits, to increase the efficiency of diagnosis. Artificial intelligence (AI) refers to the simulation of human...