For USC cancer researcher Min Yu, starting her lab meant building a culture of like-minded scientists. When she first

Positive trends in screening of patients at high risk of lung cancer may double survival in this malignancy, according to Giorgio V. Scagliotti, MD, PhD, at 2022 WCLC.

WEDNESDAY, Aug. 17, 2022 -- Cancer patients who use cannabis to relieve pain and improve appetite may be getting bad advice from dispensary staff, a new study suggests. Doctors usually offer only spotty advice about pot to their patients and,...

A team of University of Michigan researchers is developing a new anti-cancer drug that is absorbed through the gut's lymphatic system rather than blood vessels, potentially outmaneuvering the molecular signaling pathways that lead to drug resistance while increasing cancer-fighting ability and reducing side effects.

“...we don’t focus on survivorship enough. It’s important to understand the other factors involved in surviving besides just a treatment.”

A new method reveals that cancer cells can spread by rapidly applying forces to tissue material. Research to

Bacteria in our bodies bind to various host cell surface receptors, which determines where the bacteria live and how they behave. These receptors, made up of chains of sugar molecules called glycans, are more than meets the eye. Cells existing within progressive disease states like cancer can have an increased number of glycan receptors on their surfaces.

For over a century, cancer cell metabolism has been considered a paradox. New work from researchers at Washington

New structural information about an enzyme target in cancer medicine could help the development of next generation inhibitors. The enzyme, called PARP1, senses DNA damage and sends a cellular signal to carry out repair. PARP1 activity is important to many cancer types, making it an attractive target for treatments.

Findings from a recent study show that a neutrophil-to-lymphocyte ratio of less than 6 before treatment was correlated with improved overall survival for patients with endometrial cancer.

One woman is diagnosed with breast cancer every fourteen seconds somewhere across the globe -; based on data showing that an approximate 2.3 million women worldwide were newly diagnosed with breast cancer in 2020.

Results from the second interim analysis of the phase 3 TROPiCS-02 trial showed significantly improved overall survival among patients with hormone receptor-positive, HER2-negative metastatic breast cancer who were given sacituzumab govitecan vs physician’s choice of treatment.

A study coordinated by Italian researchers investigated the prognostic performance of PREDICT in patients with early-stage HER2-positive breast cancer.

For many women who have undergone chemotherapy for breast cancer, cancer-related fatigue (CRF) is a persistent side effect – and one that contributes to ongoing balance problems, suggests a paper in Rehabilitation Oncology, official journal of APTA Oncology, an academy of the American Physical Therapy Association (APTA).

The primary end point of improved progression-free survival was met in the phase 3 DESTINY-Breast02 trial when patients with HER2-positive unresectable and/or metastatic breast cancer were given trastuzumab deruxtecan vs physician’s choice of therapy.

For over a century, cancer cell metabolism has been viewed as something of a paradox. New work from researchers at Washington University in St. Louis shows that it might not be such an anomaly after all. The study is published Aug. 15 in Molecular Cell.

Valentina Boni, MD, PhD, spoke about numerous trials in the breast cancer space presented at 2022 ASCO.

The repercussions of overturning Roe v. Wade – and the failure of the Supreme Court to provide any

Cancer spreads via circulating tumor cells (CTCs) that travel through the blood to other organs, and they are

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Follow-up to the phase 2 NAVIGATE and phase 1 LOXO-TRK-14001 trials showed durable responses and extended survival in patients with NTRK fusion–positive lung cancer who were treated with larotrectinib.

Researchers from TU Delft have found a new method to efficiently make nano carriers loaded with radioactive salts for both imaging and treatment. Because the assembly of these nano carriers is incredibly simple, the innovation is very suitable for clinical research and treatments of cancer patients. The findings are now published in Advanced Therapeutics.

Research to understand how cancers grow and spread has conventionally been done on two-dimensional, flat cultures of cells, which is very different to the three-dimensional structure of cells in the body.

A research team led by Professor Park Sang-Hyun of the Department of Robotics and Mechatronics Engineering (also in charge of the Artificial Intelligence major) at DGIST (President Kuk Yang) developed a weakly supervised deep learning model that can accurately show the presence and location of cancer in pathological images based only on data where the cancer is present. Existing deep learning models needed to construct a dataset, in which the location of the cancer was accurately drawn, to specify the cancer site.

Newly designed nanoparticles can target the body's immune cells to turn them against cancer.

Researchers have developed a contact lens that can capture and detect exosomes, nanometer-sized vesicles found in bodily secretions which have the potential for being diagnostic cancer biomarkers.

Researching how cancers grow and spread has conventionally been done on two-dimensional, flat cultures of cells, which is very different to the three-dimensional structure of cells in the body. 3D cell cultures that incorporate tissue material have been developed, but the methods to measure how cancer cells use force to spread have been lacking.

Stopping children undergoing chemotherapy from feeling pain and other debilitating side-effects is the focus of research underway at The University of Queensland.

Missouri's health department on Thursday announced findings of a lengthy examination of the troubled Bridgeton Landfill in suburban St. Louis, determining that the foul odor emitting from the landfill created health problems but did not increase the risk of cancer.

Elacestrant was granted priority review by the FDA for the treatment of estrogen receptor–positive, HER2-negative metastatic breast cancer.

In a recent study with a preprint article published on bioRxiv, scientists present a novel idea how a

Scientists in the department of Advanced Organ Bioengineering and Therapeutics (Faculty of S&T, TechMed Centre) recently published a novel cancer immune therapy in the scientific journal Nature Communications. In their research, Prof Dr. Jai Prakash and his team developed newly designed nanoparticles which can target the body's immune cells to turn them against cancer.

Five Ontario-based research projects will take the next step toward advancing cancer care in the province thanks to funding from the Ontario Institute for Cancer Research (OICR).

Scientists of the department of Advanced Organ Bioengineering and Therapeutics (Faculty of S&T, TechMed Centre) recently published a novel cancer immune therapy in the scientific journal Nature Communications.

THURSDAY, Aug 11, 2022 -- Sexual dysfunction is a common side effect among women with lung cancer, a new study finds. "The SHAWL [Sexual Health Assessment in Women with Lung Cancer] study is about bringing women’s sexuality to the forefront of...

A fascinating new preprint reports the results of examining the VOC composition from individual cell cultures derived from human oral cancers, using an experimental setup employing an insect brain with attached antenna.

A new study led by researchers at the American Cancer Society (ACS) reports nearly 123,000 cancer deaths, or close to 30 percent of all cancer deaths, were from cigarette smoking in the United States in 2019, leading to more than two million Person-Years of Lost Life (PYLL) and nearly $21 billion in annual lost earnings. These losses were disproportionately higher in states with weaker tobacco control policies in the South and Midwest. The results were published today in the International Journal of Cancer.

Sometimes too much of a good thing is not good at all. Inhibiting the function of the PD-1 protein, which blocks immune function, has shown high therapeutic efficacy in cancer immunotherapy.

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A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers. This approach was successful both in vitro and in vivo. This strategy can increase chemical diversity of p53 corrector molecules for clinical development.

Celebrating those who strive to overcome disparities in cancer care to bring quality services to their patients, the Cancer Community Awards, sponsored by AstraZeneca, created the Catalyst for Equity Award.  We spoke with Dr Anne Marie Murphy, the Executive Director of Equal Hope and winner of the award in 2021, to learn more about what’s happened since her organization received the award.

Experts indicated that 77% of women with lung cancer who were surveyed reported having moderate to severe sexual dysfunction.

WEDNESDAY, Aug. 10, 2022 -- Men are known to be more likely to develop cancer than women, and a new study suggests that this is largely due to biologic differences between the sexes. “After controlling for factors like smoking, alcohol use, diet,...

Among the total number of deaths caused by different types of cancer, esophageal cancer is the sixth most significant. Several conventional treatments, such as radiotherapy, chemotherapy, and surgery...

Collagen type XII plays a key role in regulating the tumor matrix’s organization, revealing a new study from

Lumea Inc, a leader in integrated digital pathology solutions, has chosen Tempus, a leader in artificial intelligence and precision medicine, to create AI-enabled solutions that aim to significantly...

Auransa, Inc., an artificial intelligence (AI) company developing precision medicines in areas of unmet medical needs, and Polaris Quantum Biotech (Polarisqb), a quantum computing-based drug design...

WEDNESDAY, Aug. 10, 2022 -- A chemical called perfluooctane sulfate (PFOS) has been linked to the most common type of liver cancer, a new study indicates. PFOS are used in a wide range of consumer and industrial products, and are referred to as...

Caroline Boulton says there have been delays at every stage of her treatment for breast cancer.

Vanderbilt researchers have developed an active machine learning approach to predict the effects of tumor variants of unknown

Researchers at Queen's University Belfast have revealed how the pathway of an identified protein could lead to early diagnosis and targeted treatment for several cancers and brain disorders.

An Austrian study led by MedUni Vienna showed that active brain metastases in breast cancer patients are partially or even completely regressed by a novel class of drug. This is a chemical conjugate of an antibody and a chemotherapy drug that, according to current findings, opens up a completely new avenue in oncological research and targeted therapy.

Melanopsin (OPN4) is a light-sensing protein found in skin and retina cells. A new study conducted at the University of São Paulo (USP) in Brazil suggests that OPN4 can also participate in the development and progression of melanoma, the most aggressive type of skin cancer.

For women approaching menopause, a number of changes begin to occur. One of the most common is an increase in obesity, which, in turn, raises the risk for breast cancer after menopause.

About 53% of lung cancers in females are not attributable to smoking worldwide and a new model presented today at the IASLC World Conference on Lung Cancer may allow clinicians the ability to assess and stratify lung cancer risk in female non-smokers in China.

Researchers from Vancouver, British Columbia examine the effect of duration of past exposure to air pollution with lung cancer diagnosis.

Sexual dysfunction is highly prevalent in women with lung cancer with most survey participants reporting little to no interest in sexual activity, according to research led by Narjust Florez (Duma), MD, associate director for the Cancer Care Equity Program at Dana-Farber Cancer Institute.

The understanding of the link between common genetic mutations and certain cancers is increasing.

Although it has long been known that predicting outcomes in cancer patients necessitates taking into account a variety of characteristics, including patient history, genes, and disease pathology,...

About 15 years ago, a group of researchers discovered mutant zebrafish. The eyes of these zebrafish did not develop correctly, resulting in significantly smaller eyes than those of wild zebrafish. Now, one of these researchers—Prof. Ichiro Masai—who leads the Developmental Neurobiology Unit at the Okinawa Institute of Science and Technology (OIST), alongside his former Ph.D. student Dr. Swathy Babu, has used this mutation to understand the role of a protein in preventing cell death. This could have vast implications for the development of cancer therapy and for understanding how the cell cycle is regulated.

The singer and actress spent years raising money to fund cancer research.

A five-year, $2.7 million grant from the National Cancer Institute will help provide answers. The goal: Improve survival

While it's long been understood that predicting outcomes in patients with cancer requires considering many factors, such as patient history, genes and disease pathology, clinicians struggle with integrating this information to make decisions about patient care.

Patients with lung cancer who attended a lung cancer screening event and who then participated in a personalized smoking cessation study achieved smoking abstinence rates of more than 30 percent, according to research presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

The protocol used to screen and detect lung cancer in the NELSON Trial is more sensitive than the protocol used in the National Lung Cancer Screening Trial, particularly for early-stage cancers, according to research reported today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

Younger patients with lung cancer are significantly more likely than older patients to be diagnosed with later stages of disease, illustrating the need to develop strategies to increase the early detection of lung cancer among younger patients who are currently ineligible for lung cancer screening.

Rates of most types of cancer are higher in men than in women for reasons that are unclear. Results from a recent study published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, suggest that the cause may be underlying biological sex differences rather than behavioral differences related to smoking, alcohol use, diet, and other factors.

Studying a deadly type of breast cancer called triple negative, Johns Hopkins Medicine scientists say they have identified key molecular differences between cancer cells that cling to an initial tumor and those that venture off to form distant tumors.

The biochemist Nick Lane thinks life first evolved in hydrothermal vents where precursors of metabolism appeared before genetic information. His ideas could lead us to think differently about aging and cancer. The post A Biochemist’s View of Life’s Origin Reframes Cancer and Aging first appeared on Quanta Magazine

MONDAY, Aug. 8, 2022 -- Women with breast cancer commonly see their sexual health decline, yet their doctors aren't telling them what to expect -- or what to do about it. Those are among the findings of a new study that asked breast cancer patients...

MONDAY, Aug. 8, 2022 – Smoking and older age are the two most important risk factors for cancer, a new, large study shows. The researchers also said doctors should look at excess body fat, family history and several other factors to help patients...

Researchers at Case Western Reserve University and the University of Washington expect to gain valuable new insights into highly aggressive prostate cancer by combining artificial intelligence...

Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and how science impacts upon all aspects of society and life.

A clinical trial is only as powerful as its participants. For years, researchers have struggled to fill clinical trials and enroll sufficiently diverse groups of patients for results to reflect the broader population, in part because of stringent guidelines on who can participate.

The goal: Improve survival rates for lung cancer patients. The question researchers want to answer: Are there new ways to determine the best treatment for these patients?

Researchers at Michigan State University have shown that locusts can not only "smell" the difference between cancer cells and healthy cells, but they can also distinguish between different cancer cell lines.

The increase was seen across all cancer types, except prostate cancer, and hit those with hematologic cancers the hardest, according to a new National Inpatient Sample analysis.

The European Commission approved olaparib as monotherapy or in combination with endocrine therapy for patients with germline BRCA1/2-mutant, HER2-negative high-risk early breast cancer.

Researchers at Michigan State University have shown that locusts can not only "smell" the difference between cancer cells and healthy cells, but they can also distinguish between different cancer cell lines. 

Based on results from the phase 3 DESTINY-Breast04 trial, the FDA has approved fam-trastuzumab deruxtecan-nxki as an intravenous infusion for patients with unresectable or metastatic HER2-low breast cancer.

FRIDAY, Aug. 5, 2022 -- Most sexually active people will contract the human papillomavirus (HPV) during their lifetimes, and about 90% will clear it from their bodies. But some women are susceptible to the cervical lesions that infection brings,...

Supported by data from an ongoing phase 2 trial, the ROS1 inhibitor taletrectinib was granted breakthrough therapy designation for the treatment of certain patients with advanced or metastatic ROS1-positive non–small cell lung cancer.

Brykyta Shelton found herself standing in a checkout line of a big-box retailer, uncomfortably aware as a woman ahead of her stared at her sandaled feet.

FRIDAY, Aug. 5, 2022 -- Elevated levels of a specific protein appear to be linked to an increased risk of developing diabetes and dying from cancer, a new study finds. High levels of prostasin -- mainly found in epithelial cells, which line the...

A viral TikTok with millions views about how tampons that contain titanium dioxide can cause cancer and other health problems has spurred calls on the platform to throw away all products that match that description. Before you start gathering all your tampons and scouring their ingredient lists, you should know that… Read more...

Men with early, curable stages of prostate cancer are missing opportunities to have their cancer detected because national

Metastatic bladder cancer is generally incurable, so new therapies are an urgent need. Researchers at the University of Alabama at Birmingham now report a potential treatment for a quarter of bladder cancers.

Children's Hospital of Philadelphia has helped launch a new computational platform that will harmonize pediatric cancer data, allowing researchers, pharmaceutical companies, and advocacy groups to accelerate the pace of drug development for pediatric cancer.

To identify oral and throat cancer, lesions have to be big enough for doctors to see. A saliva test could enable much earlier diagnosis

A research team from the lab of Quing Zhu, the Edwin H. Murty Professor of Engineering in the Department of Biomedical Engineering at the McKelvey School of Engineering at Washington University in St. Louis, has combined optical coherence tomography (OCT) and machine learning to develop a colorectal cancer imaging tool that may one day improve the traditional endoscopy currently used by doctors.

THURSDAY, Aug. 4, 2022 -- People who’ve had chemotherapy to treat a range of common cancers should also have a hearing test. In a new study of 273 cancer survivors, researchers found more than half experienced significant hearing loss even if they...

To investigate the long-term benefit of hormone-lowering treatment, researchers at Karolinska Institutet have done a 20-year follow-up of

Researchers at Queen's University Belfast have received funding from Breast Cancer Now to search for new treatments inspired by COVID-19 vaccine innovation.

Investigators from Cedars-Sinai Cancer have identified genetic signatures that could predict whether tumors in patients with bladder and other cancers will respond to immunotherapy.

Celebrating those who are making a patient’s experience as easy as possible during an extraordinarily difficult time, the Cancer Community Awards, sponsored by AstraZeneca, presents an individual or organization with a Catalyst for Care Award. We spoke with the 2021 winner, Unite for HER’s founder and CEO, Sue Weldon, to hear more about what’s happened since her organization received the award.

A new large study led by researchers at the American Cancer Society (ACS) shows older age and smoking are the two most important risk factors associated with a relative and absolute five-year risk of developing any cancer.

Turning down the thermostat seems to make it harder for cancer cells to grow, according to a study in mice by researchers at Karolinska Institutet in Sweden.

As the number of cancer survivors rises, primary care specialists are playing an increasingly important role in managing these patients.